Mass Spectrometry

The cores listed below are located at Harvard Medical School, affiliated institutions or other Harvard Schools. 

Analytical Chemistry Core

In the Analytical Chemistry Core at HMS there is an Agilent 6530 QTOF LCMS and an Agilent 6130 Single Quad LCMS available for use by investigators who can operate them independently, running their own samples and interpreting the results.

Core Director - Matt Henke
Core Website - http://iccb.med.harvard.edu/analytical-chemistry-core

Thermo Fisher Center for Multiplexed Proteomics

The Thermo Fisher Center offers quantitative protein expression profiling. The Center uses high resolution mass spectrometer (Orbitrap Fusion™ Tribrid™ Mass Spectrometer) and isobaric tandem mass tags (TMT) to quantify protein or phosphopeptide expression from cells, tissues or immunoprecipitated protein samples. Currently the TMT technology allows for the analysis of 6 - 11 samples within a single experiment by sample multiplexing. This allows us to study several conditions in a single experiment. The services are provided to the HMS community as well as external users.

Core Director - Prof. Steven P. Gygi
Core Website - http://tcmp.hms.harvard.edu/

Taplin Biological Mass Spectrometry Facility

The Taplin Biological Mass Spectrometry facility provides mass spectrometry services to members of the HMS community as well as external users.

Core Director - Ross Tomaino
Core Website - http://taplin.med.harvard.edu/

Small Molecule Mass Spectrometry Core at FAS