Mass Spectrometry

The cores listed below are located at Harvard Medical School, affiliated institutions or other Harvard Schools. 

Analytical Chemistry Core

In the Analytical Chemistry Core at HMS there is an Agilent 6530 QTOF LCMS and an Agilent 6130 Single Quad LCMS available for use by investigators who can operate them independently, running their own samples and interpreting the results.

Core Director - Tom Wyche
Admin Contact - Katrina Rudnicki
Core Website - http://iccb.med.harvard.edu/analytical-chemistry-core

Thermo Fisher Center for Multiplexed Proteomics

The Thermo Fisher Center offers proteome-wide protein expression profiling. The Center uses recently-introduced high resolution mass spectrometers (Orbitrap Fusion Tribrid) and isobaric tandem mass tags (TMT) to quantify protein expression from cells or tissues. Currently the tandem mass tag technology allows for the analysis of 6-10 samples within a single experiment.  For example, protein expression in a cancer cell line can be profiled after nine drug treatments and compared to an untreated sample across >6,000 proteins.  The services are provided to the HMS community as well as external users.

Core Director - Ryan Kunz
Core Website - http://tcmp.hms.harvard.edu/

Taplin Biological Mass Spectrometry Facility

The Taplin Biological Mass Spectrometry facility provides mass spectrometry services to members of the HMS community as well as external users.

Core Director - Ross Tomaino
Core Website - http://taplin.med.harvard.edu/

Small Molecule Mass Spectrometry Core at FAS